Anti-cancer compositions and methods

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United States of America Patent

PATENT NO 9126911
APP PUB NO 20130184340A1
SERIAL NO

13785778

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Abstract

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Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.

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Patent Owner(s)

  • THE PENN STATE RESEARCH FOUNDATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amin, Shantu G Union City, US 11 156
Desai, Dhimant H Mechanicsburg, US 10 155
Robertson, Gavin P Hummelstown, US 25 385
Sharma, Arati K Hummelstown, US 12 197
Sharma, Arun K Hummelstown, US 37 345

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