Uridine diphosphate-dependent glycosyltransferase enzyme

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United States of America Patent

PATENT NO 11788070
SERIAL NO

17495139

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Abstract

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In various aspects, the present invention provides uridine diphosphate-dependent glycosyltransferase (UGT) enzymes capable of catalyzing the transfer of a monosaccharide moiety from a NDP-sugar to the 3′ carbon of a sugar moiety of a substrate, such as a terpenoid glycan, thereby functioning as a “1-3 UGT.” In other aspects, the invention provides polynucleotides encoding the 1-3 UGT, and host cells comprising the same. In still other aspects, the invention provides methods for preparing glycosylated substrates, including steviol glycosides, using the enzyme and host cells of this disclosure.

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Patent Owner(s)

  • MANUS BIO INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donald, Jason Eric Watertown, US 7 6
Kumaran, Ajikumar Parayil Lexington, US 33 62
Love, Aaron Cambridge, US 13 53
Santos, Christine Nicole S Newton, US 25 15
Toomey, Christopher Cambridge, US 11 256

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