Pulmonary administration of chemically modified insulin
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United States of America Patent
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Jan 4, 2005
Grant Date -
Jun 26, 2003
app pub date -
May 21, 2002
filing date -
May 21, 2001
priority date (Note) -
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Abstract
The present invention provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable for delivery to the lung and exhibit pharmakokinetic and/or pharmacodynamic properties that are significantly improved over native insulin.
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