Anthracycline glycosides from streptomyces

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United States of America Patent

PATENT NO 4192915
SERIAL NO

05898065

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Abstract

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New antitumor agents designated rhodirubin A and B, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria and mammalian tumors, are produced by fermentation of rhodirubin-producing strains of Streptomyces, e.g. Streptomyces sp. ME 505-HEI (ATCC 31273).

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Patent Owner(s)

  • BRISTOL-MYERS SQUIBB COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hamada, Masa Hoya, JP 39 224
Inui, Taiji Chigasaki, JP 24 213
Ishizuka, Masaaki Tokyo, JP 31 113
Naganawa, Hiroshi Tokyo, JP 34 378
Oki, Toshikazu Kamakura, JP 54 277
Takeuchi, Tomio Tokyo, JP 164 836
Umezawa, Hamao Tokyo, JP 141 773

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