Method and device for detecting bright spots on image, and computer program product

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United States of America Patent

PATENT NO 11847766
APP PUB NO 20210217177A1
SERIAL NO

17270413

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Abstract

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A method and device for detecting bright spots on an image. The image is acquired from a field of view where a base extension reaction occurs, multiple nucleic acid molecules with optically detectable labels exist in the field of view where the base extension reaction occurs, and at least some of the nucleic acid molecules appear as bright spots on the image. The method includes preprocessing the image to obtain a preprocessed image; determining a critical value to simplify the preprocessed image to obtain a simplified image, determining a first bright spot detection threshold on the basis of the preprocessed image, and identifying candidate bright spots on the image on the basis of the preprocessed image and the simplified image, including determining a pixel matrix that satisfies at least two of conditions as a candidate bright spot.

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Patent Owner(s)

Patent OwnerAddress
GENEMIND BIOSCIENCES COMPANY LIMITED5TH & 6TH F 2ND BLK SHENYE JINYUAN BLDG NO 116 QINGSHUI RIVER 1ST RD LUOHU DISTRICT SHENZHEN CITY GUANGDONG 518000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jiang, Zefei Shenzhen, CN 18 3
Jin, Huan Shenzhen, CN 25 41
Li, Linsen Shenzhen, CN 15 123
Xu, Weibin Shenzhen, CN 8 1
Yan, Qin Shenzhen, CN 29 20
Zhou, Zhiliang Shenzhen, CN 16 3

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