Stem cells that transform to beating cardiomyocytes

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United States of America Patent

PATENT NO 7220582
SERIAL NO

10863004

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein is a novel isolated population of stem cells, called spoc cells, that can be induced, either in vivo or in vitro, to differentiate into cardiomyocytes. Methods are disclosed herein to differentiate the spoc cells, and to utilize these spoc cells for screening agents that affect cardiomyocytes. Methods are also provided herein to utilize spoc cells in therapeutic applications for the treatment of myocardial defects, such as areas of ischemic or traumatic damage.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Epstein, Neal D Chevy Chase, MD 6 49
Gopal, Thiru V North Potomac, MD 6 45
Hassanzadeh, Shahin Fairfax, VA 6 49
Winitsky, Steve O Bethesda, MD 5 45

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