Isoquinoline derivatives
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United States of America Patent
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Jan 17, 1989
Grant Date -
N/A
app pub date -
Apr 21, 1987
filing date -
Nov 12, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An isoquinoline derivative represented by the formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and A are as defined in the disclosure, or a pharmacologically acceptable acid salt thereof. These compounds have an excellent relaxation action on blood vessels, particularly coronary arteries, and on bronchial tubes. Accordingly, the compounds can be advantageously utilized as drugs for prevention and treatment of angina, myocardial infarction, cardiovascular thrombosis, cerebrovascular thrombosis, hypertonia, asthma and other various circulatory and respiratory organ diseases.
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