Growth differentiation factor 15 as biomarker for metformin

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11807905
APP PUB NO 20210254156A1
SERIAL NO

17198781

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to metformin for use in treating a patient, wherein the patient exhibits an increased level of GDF15 in response to metformin treatment; to methods of identifying a patient who will benefit or who will not benefit from metformin treatment; methods of treating a patient at risk of developing or suffering from a disease or disorder comprising administering therapeutically effective amount of metformin; methods of adapting the dosage of metformin; the usage of GDF15 as biomarker for identifying a patient who will benefit or who will not benefit from metformin treatment, kits for use in identifying a patient who will benefit from metformin treatment and the use of the kits, as well as methods of treating a patient or who will not benefit from metformin treatment.

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Patent Owner(s)

  • SANOFI-AVENTIS DEUTSCHLAND GMBH; MCMASTER UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gerstein, Hertzel Toronto, CA 21 96
Hess, Sibylle Frankfurt am Main, DE 7 15
Pare, Guillaume Puslinch, CA 6 5
Sadowski, Thorsten Frankfurt am Main, DE 16 15
Steinberg, Gregory Ancaster, CA 5 2

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