Modular, multifunctional nanoparticle-based bioconjugate for realtime visualization of cellular membrane potential

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11287430
APP PUB NO 20200355696A1
SERIAL NO

16894920

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dawson, Philip E San Diego, US 15 218
Delehanty, James B Washington, US 23 75
Deschamps, Jeffrey R Laurel, US 20 74
Efros, Alexander L Annandale, US 7 0
Field, Lauren D College Park, US 4 0
Huston, Alan L Aldie, US 34 566
Medintz, Igor L Springfield, US 38 170
Nag, Okhil Alexandria, US 6 0
Oh, Eunkeu Alexandria, US 14 27
Stewart, Michael H Springfield, US 16 53
Susumu, Kimihiro Alexandria, US 23 61

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Sep 29, 2025
7.5 Year Payment $3600.00 $1800.00 $900.00 Sep 29, 2029
11.5 Year Payment $7400.00 $3700.00 $1850.00 Sep 29, 2033
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00