Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases

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United States of America Patent

PATENT NO 11958871
APP PUB NO 20200392174A1
SERIAL NO

16971618

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to novel compounds which are particularly useful as inhibitors of bacterial glutaminyl cyclases (bacQC); pharmaceutical compositions comprising such compounds; compounds and/or pharmaceutical compositions for use in methods for treatment, in particular for use in the treatment of periodontitis and related conditions; as well as to crystals comprising bacterial glutaminyl cyclases, methods for identifying candidate compounds which may associate with the binding pocket of a bacQC and/or are bacQC inhibitors.

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Patent Owner(s)

  • FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buchholz, Mirko Halle, DE 25 324
Cynis, Holger Halle, DE 20 87
Geissler, Stefanie Halle, DE 1 0
Jäger, Christian Halle, DE 4 2
Liebe, Linda Halle, DE 1 0
Linnert, Miriam Halle, DE 1 0
Meitzner, Diane Wolfen, DE 1 0
Piechotta, Anke Halle, DE 4 5
Ramsbeck, Daniel Halle, DE 14 41

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