Agonists of toll-like receptor 3 and methods of their use

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United States of America Patent

PATENT NO 8492358
APP PUB NO 20120034248A1
SERIAL NO

13168494

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Abstract

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TLR3 agonist compounds, compositions and methods are provided for stimulating the activity of TLR3. The compositions comprise oligonucleotide-based compounds that bind to and activate TLR3. The compositions may also comprise oligonucleotide-based compounds that bind to and activate TLR3 in combination with other therapeutic and/or prophylactic compounds and/or compositions. Methods of using these compounds and compositions for stimulation of TLR3 activity and for prevention or treatment of diseases wherein modulation of TLR3 activity would be beneficial are provided.

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Patent Owner(s)

  • IDERA PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agrawal, Sudhir Shrewsbury, US 222 8115
Kandimalla, Ekambar Southborough, US 59 770
Lan, Tao Winchester, US 13 141
Philbin, Victoria Jane Boston, US 1 3

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