Cyclic AMP-specific phosphodiesterase inhibitors
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United States of America Patent
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Feb 14, 2006
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N/A
app pub date -
Jan 15, 2004
filing date -
Dec 23, 1999
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Abstract
Novel pyrrolidine compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
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