Mg alloy mesh reinforced polymer/ECM hybrid scaffolds for critical-sized bone defect regeneration

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United States of America Patent

PATENT NO 11904069
APP PUB NO 20210187158A1
SERIAL NO

16498035

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Abstract

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The invention relates to biomimetic, biodegradable composites including a magnesium (Mg) alloy mesh and a polymer/extracellular matrix (ECM). These hybrid composites, more particularly, are useful for the fabrication of medical implant devices, e.g., scaffolds, and are effective for bone regeneration. The fabrication process includes creating the Mg alloy mesh, and concurrently electrospinning the polymer and electrospraying the ECM onto the mesh.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION130 THACKERAY AVENUE 1ST FLOOR GARDNER STEEL CONFERENCE CENTER PITTSBURGH PA 15260

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yingqi Pittsburgh, US 2 0
Shanov, Vesselin Cincinnati, US 5 49
Wagner, William R Gibsonia, US 104 4242
Ye, Sang-Ho Cheswick, US 4 16

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