PAI-2 conjugates for the treatment and imaging of cancer
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United States of America Patent
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Jun 16, 2009
Grant Date -
Jan 3, 2002
app pub date -
Feb 23, 2001
filing date -
Feb 24, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises PAI-2 or a functional derivative, homologue, analogue, chemical equivalent or mimetic thereof, which PAI-2 is bound, linked, or otherwise associated with a toxin or label.
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