Orally distintegrating formulation and process for preparing the same
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United States of America Patent
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Oct 19, 2010
Grant Date -
Apr 26, 2007
app pub date -
Apr 30, 2005
filing date -
Apr 30, 2004
priority date (Note) -
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Abstract
An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegrate rapidly in oral cavity and be taken without aid of water; Moreover, the formulation has a low hygroscopicity, so that the requirements for storing or producing the formulation is decreased, and the storage life is elongated to facilitate the administration by a patient and the preparation of the protein and vaccine drugs.
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