Methods for assaying percentage of glycated hemoglobin

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United States of America Patent

PATENT NO 7855079
SERIAL NO

11881179

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The methods utilizes one or two different types of oxidizing agents which selectively oxidize low-molecular weight reducing substances and high-molecular weight (mainly hemoglobin) reducing substances in blood samples, coupled with enzymatic reactions catalyzed by proteases, fructosyl amino acid oxidase, and peroxidase. The invention provides kits for performing the methods of the invention.

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Patent Owner(s)

  • DIAZYME LABORATORIES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Datta, Abhijit Carlsbad, US 13 122
Liu, Limin San Diego, US 48 550
Yuan, Chong-Sheng San Diego, US 39 208

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