Polymer conjugates of mutated neublastin
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United States of America Patent
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Oct 28, 2008
Grant Date -
Jun 30, 2005
app pub date -
Jan 31, 2003
filing date -
Feb 1, 2001
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Abstract
A dimer comprising a mutated neublastin polypeptide coupled to a polymer is disclosed. Such dimers exhibit prolonged bioavailability and, in preferred embodiments, prolonged biological activity relative to wild-type forms of neublastin.
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