Method of sensing chemical and bio-molecular analytes and sensing system using a microcantilever
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United States of America Patent
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Aug 28, 2012
Grant Date -
Jul 8, 2010
app pub date -
Nov 27, 2007
filing date -
Nov 27, 2006
priority date (Note) -
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Abstract
Methods and systems of detecting analytes using a microcantilever system are generally described. The microcantilever system generally includes micro- or nano-sized elements that can be electrostatically driven to resonance. Utilizing the disclosed devices and methods, direct electronic detection of the resonant frequency, changes of the resonant frequency, and associated phase signal of a micro- or nano-sized element can be utilized to measure the presence of a targeted analyte. The detection system of the present invention utilizes a non-contact microcantilever device. That is, the surface of the microcantilever (e.g., the surface of the resonating beam) does not bond or otherwise attach to an analyte or other chemical. Thus, the microcantilever device, including the resonating beam, can be kept in pristine condition during and even after repeated use.
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