Targeted radioimmunotherapy
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United States of America Patent
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Jul 20, 1999
Grant Date -
N/A
app pub date -
Apr 1, 1997
filing date -
Apr 1, 1997
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A stent for the inhibition of restentosis. The stent is coated with an antigen which can be bound by a labelled antibody. The antibody is preferably labelled with a radioactive source. After the stent has been placed in the blood vessel of the subject, the antibody is injected. The antibody then binds to the antigen on the stent, thereby localizing the radioactive source to the area to be treated, for example for restenosis. Other biomedical devices, such as coil, artificial valve and vascular graft, could also be used in the place of the stent. The biomedical device could be placed in another biological passageway, such as the gastrointestinal tract, an airway or the genitourinary tract.
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