Open bore electrode with a tiered drug therapy delivery system
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United States of America Patent
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Mar 14, 2000
Grant Date -
N/A
app pub date -
Oct 30, 1998
filing date -
Oct 30, 1998
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Abstract
An implantable cardiac stimulation lead comprises an elongated electrical conductor with an electrode configured to deliver a tiered level of drug therapy to a patient. An insulative electrical sheath covers the electrical conductor and an electrical connector is coupled to the proximal end of the electrical conductor, adapted for connection with the pulse generator. An electrically conductive electrode is located at a distal end of the electrical conductor whose proximal end is adapted for connection to an implantable stimulation device, the electrode having an interior cavity and an axial bore extending between an exterior surface and the interior cavity. A matrix member, preferably composed of silicon rubber, is received within the interior cavity and contains a therapeutic drug. The exterior surface is coated and the bore is filled with a therapeutic drug-hydrophilic wetting agent compound and the bore is filled with a wetting agent compounded with the therapeutic drug such that tiered delivery to a recipient of the therapeutic drug is achieved first from the exterior electrode surface, then from the bore, and finally from the matrix member. The opening of the bore at the exterior surface of the electrode is between about 0.1% and 50% of the entire surface area of the electrode and is insufficient to allow the intrusion of body fluid from the recipient into the cavity in the absence of a wetting agent, a hydrophilic, water soluble, biocompatible polymer. The diameter of the bore is between about 0.001 inches and 0.035 inches.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
- PACESETTER, INC.
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Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Vachon, David J | Granada Hills, CA | 30 | 4248 |
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Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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