Salts
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United States of America Patent
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Sep 25, 2007
Grant Date -
Oct 20, 2005
app pub date -
May 27, 2003
filing date -
May 31, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
There is provided pharmaceutically-acceptable acid addition salts of compounds of formula I, ##STR00001## wherein R.sup.1 represents C.sub.1-2 alkyl substituted by one or more fluoro substituents; R.sup.2 represents C.sub.1-2 alkyl; and n represents 0, 1 or 2, which salts are useful as prodrugs of competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
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