Neurotoxins with enhanced target specificity

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United States of America Patent

PATENT NO 7273722
SERIAL NO

09726949

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Abstract

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Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood.

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Patent Owner(s)

  • ALLERGAN, INC.;ALLERGAN SALES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoki, Kei Roger Coto de Caza, CA 187 3993
Lin, Wei-Jen Cerritos, CA 14 160
Steward, Lance E Irvine, CA 134 2601

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