Enzymatic method for preparation of UDP-galactose

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United States of America Patent

PATENT NO 11739358
APP PUB NO 20220389469A1
SERIAL NO

17755650

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Abstract

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The present invention relates to an enzyme-catalyzed process for producing UDP-galactose from low-cost substrates uridine monophosphate and D-galactose in a single reaction mixture. The process can be operated (semi)continuously or in batch mode. The process can be extended to uridine as starting material instead of uridine monophosphate. Further, the process can be adapted to produce galactosylated molecules and biomolecules including saccharides, proteins, peptides, glycoproteins or glycopeptides, particularly human milk oligosaccharides (HMO) and (monoclonal) antibodies.

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Patent Owner(s)

Patent OwnerAddress
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E VHOFGARTENSTRASSE 8 MÜNCHEN 80539

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mahour, Reza Leipzig, DE 4 0
Rexer, Thomas F T Magdeburg, DE 3 0

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