Preparation of substituted 2-aminopyrazines

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United States of America Patent

PATENT NO 4211870
SERIAL NO

06027630

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Abstract

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Preparation of substituted 2-aminopyrazines by reaction of an .alpha.-chloro or .alpha.-bromo oxime with an aminoacetonitrile in the presence of an acid-uptake agent, followed by separation of the intermediate novel hydroxyimino-substituted aminoacetonitrile, and cyclization thereof with acid.

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Patent Owner(s)

  • ELI LILLY AND COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barnett, Charles J Indianapolis, IN 27 101
Emmick, Thomas L Greenfield, IN 1 4
Hoying, Richard C Indianapolis, IN 5 15

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