Chimeric genome engineering molecules and methods

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11293019
APP PUB NO 20210054362A1
SERIAL NO

16955639

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Abstract

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The present disclosure provides compositions and methods for increasing mutation efficiency and homologous recombination rates of site-specific endonucleases. The compositions and methods comprise a chimeric polypeptide comprising a site-specific endonuclease or a domain thereof and a functional moiety. The current inventions relate to functional enhancement of the CRISPR-Cas enzymes. Disclosed herein include possible variants and their intended improvements.

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Patent Owner(s)

  • GFLAS LIFE SCIENCES, INC.; SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choe, Sunghwa Seoul, KR 23 22
Choi, Sunmee Seoul, KR 3 78
Kim, Dong Wook Seoul, KR 294 1571
Lee, Jung Hyuk Seoul, KR 21 206
Lim, Junghak Seoul, KR 2 2
Park, Aiden Y Seoul, KR 4 2
Park, Jongjin Seoul, KR 32 94
Park, Mijin Seoul, KR 18 56
Park, Slki Seoul, KR 4 2
Yoon, Ji Young Seoul, KR 9 99

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