Pantoprazole multiparticulate formulations
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United States of America Patent
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Jun 30, 2009
Grant Date -
Aug 23, 2007
app pub date -
Mar 30, 2007
filing date -
Oct 1, 2003
priority date (Note) -
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Abstract
A method of treating gastroesophageal reflux disease (GERD), ulcers of the stomach or duodenum, or Zollinger-Ellison Syndrome in a human, by administering pantoprazole sodium multiparticulates is described. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a disintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the subcoat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.
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