Isolation and structure of spongistatins 5,7,8 and 9
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United States of America Patent
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Feb 28, 1995
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N/A
app pub date -
Jul 2, 1993
filing date -
Jul 2, 1993
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Abstract
A Southwest Indian Ocean marine sponge Spirastrella spinispirulifera (bri colored reds and purples) has been found to contain new and exceptionally active cell (human cancer) growth inhibitors spongistatin 5, spongistatin 7, spongistatin 8 and spongistatin 9. These compositions are related to spongistatin 1, which was found in a black Spongia sp. in the Porifera family. A method of treating human cancer cells with spongistatin 5 and spongistatin 7 is also disclosed.
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