Process for the preparation of fluorosteroids
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United States of America Patent
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Sep 21, 2004
Grant Date -
May 23, 2002
app pub date -
May 16, 2001
filing date -
Nov 17, 2000
priority date (Note) -
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Abstract
Described herein is a process for the preparation of 6.alpha.-fluorosteroids of formula (I), in which R is chosen from H, OH and an alkyl group with from 1 to 4 carbon atoms and R' is a carboxyalkyl group with from 1 to 4 carbon atoms in the alkyl chain, comprising the selective fluorination at the 6.alpha.-position ##STR1## by treatment of the compound of formula (III), wherein R and R' are as defined above, with an electrophilic fluorinating agent.
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