Environmentally sensitive compositions comprising a pH-triggered membrane protein and methods of use thereof in the treatment and diagnosis of tumors

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11229710
APP PUB NO 20180221500A1
SERIAL NO

15810830

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Abstract

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An environmentally sensitive membrane binding polypeptide, pH (low)-sensitive membrane peptide (pHLIP) has improved insertion kinetics balanced with solubility to selectively target acidic tissues.

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Patent Owner(s)

  • UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES; YALE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andreev, Oleg A South Kingstown, US 24 114
Engelman, Donald M New Haven, US 25 253
Reshetnyak, Yana K South Kingstown, US 25 114

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