Useful mutations of bacterial alkaline protease
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United States of America Patent
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Dec 28, 2004
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N/A
app pub date -
Dec 5, 2002
filing date -
Jan 7, 1988
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Expired
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Abstract
The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.
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