Matching thermally modulated variable restrictors to chromatography separation columns

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United States of America Patent

PATENT NO 11733216
APP PUB NO 20200333301A1
SERIAL NO

16917178

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Abstract

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Thermally modulated variable restrictors used in chromatography systems enable independent control of system pressure and linear velocity of a compressible mobile phase passing through a chromatography column. A method for configuring a chromatography system with independent control of system pressure and mass flow rate of a compressible mobile phase includes determining a type of chromatography separation column to be used in the chromatography system, matching a thermally modulated variable restrictor to the type of chromatography separation column for use together during operation of the chromatography system, and bundling the chromatography column with its matching thermally modulated variable restrictor for distribution as a single package.

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Patent Owner(s)

  • WATERS TECHNOLOGIES CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fogwill, Michael O Uxbridge, US 62 70
Gerhardt, Geoff Woonsocket, US 8 10
Michienzi, Joseph D Plainville, US 72 203
Murphy, James P Franklin, US 58 1864

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