Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic
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United States of America Patent
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May 27, 1997
Issued Date -
N/A
app pub date -
May 16, 1995
filing date -
Apr 24, 1992
priority date (Note) -
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Abstract
A synergistic pharmaceutical combination or composition is disclosed for the treatment of gastritis and peptic ulcer containing a therapeutic amount of a histamine H.sub.2 receptor blocking agent, which increases intragastric pH, and an acid degradable antibacterial compound. In particular, the combination is directed to the treatment of infections by Helicobacter pylori by raising the bioavailability of acid degradable antibacterial compounds.
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