Process and composition for reducing blood pressure

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United States of America Patent

PATENT NO 4269827
SERIAL NO

06162082

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Abstract

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A blood pressure reducing composition which inhibits renin in vivo which composition has the peptide structure Z-His-Pro-Phe-His-X-X-Val-Tyr-Y wherein the xs are the same or different and are phenylalanine, a chlorinated phenylalanine or tyrosine, Y is a charged amino acid and Z is proline or polyproline having up to 5 prolyl residues.

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Patent Owner(s)

  • MASSACHUSETTS GENERAL HOSPITAL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burton, James A Amesbury, MA 18 269
Haber, Edgar Weston, MA 34 483

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