Method of inhibiting growth or survival of a cell by providing an anti-108P5H8 antibody
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United States of America Patent
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Mar 31, 2009
Grant Date -
N/A
app pub date -
Oct 25, 2002
filing date -
Dec 15, 2000
priority date (Note) -
Expired
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Abstract
A novel gene (designated 108P5H8) and its encoded protein, and variants thereof, are described wherein 108P5H8 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 108P5H8 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 108P5H8 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 191P1E1B can be used in active or passive immunization.
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