Gamma delta CAR-T cells comprising Fc gamma intracellular signaling domains

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United States of America Patent

PATENT NO 11890302
APP PUB NO 20200289564A1
SERIAL NO

16649982

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to gamma delta (γδ) T cells and/or Natural Killer (NK) cells expressing constructs to provide for the expression of a Chimeric Antigen Receptor (CAR) incorporating the signalling domain of FCY Receptors. Suitably the invention also relates to constructs to provide such CARs and methods for introducing such CARs into cells and expressing such CARs in cells comprising receptors of gamma delta (γδ) T cells and/or Natural Killer (NK) cells.

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Patent Owner(s)

  • TC BIOPHARM LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cosimo, Emilio Holytown Motherwell, GB 2 2
London, Timothy Holytown Motherwell, GB 3 2
Patakas, Agapitos Holytown Motherwell, GB 4 4

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