Mutations affecting carotenoid production
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United States of America Patent
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Jun 19, 2007
Grant Date -
Jul 29, 2004
app pub date -
Dec 12, 2003
filing date -
Dec 19, 2002
priority date (Note) -
Expired
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Abstract
Mutations in genes having no direct relationship to the carotenoid biosynthetic pathway have been found to increase carbon flux through that pathway. Complete disruption in the deaD, mreC, and yfhE genes were effective. Additionally where genes of the lower carotenoid pathway reside on a plasmid having either a p15A or pMB1 replicon, mutations in the thrS, rspA, rpoC, yjeR, and rhoL were found effective.
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