Dinuclear copper-based compound and ligand for nucleic acid scission and anticancer treatment

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United States of America Patent

PATENT NO 7390832
APP PUB NO 20050148662A1
SERIAL NO

10492197

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Abstract

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The present invention is related to a novel method for oxidizing or splitting nucleic acids at specific points on a complementary nucleic acid segment using a dinuclear copper-based compound of Formula I. Additionally, the present invention is related to a novel treatment of cancer, tumors, and cancer cells using a dinuclear copper-based compound of formula I or a naked ligand of Formula II.

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Patent Owner(s)

  • THE JOHNS HOPKINS UNIVERSITY;UNIVERSITY OF MARYLAND, BALTIMORE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Karlin, Kenneth D Owings Mills, MD 3 5
Li, Lei Baltimore, MD 580 3601
Murthy, Narasimha N Madras, IN 2 5
Rokita, Steven E Sliver Spring, MD 12 271

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