Compositions for the treatment of pigmentation disorders and methods for their manufacture
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United States of America Patent
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Nov 15, 2005
Issued Date -
N/A
app pub date -
Apr 14, 2003
filing date -
May 23, 2001
priority date (Note) -
Expired
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Abstract
The present invention addresses the problem of excessive discoloration in hydroquinone compositions of a neutral pH. Antioxidants in the hydroquinone phase and inorganic or amino acyl cationic salts of acidic ascorbyl esters, preferably sodium metabisulfite and magnesium ascorbyl phosphate respectively, are effective in stabilizing such hydroquinone compositions, which are used in treatment of pigmentation disorders. Protected retinoid may be added to these compositions for additional skin benefit effects.
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