Method for purifying active polypeptides or immunoconjugates

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United States of America Patent

PATENT NO 11136396
APP PUB NO 20200231680A1
SERIAL NO

16786634

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Abstract

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The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

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Patent Owner(s)

  • MEDIMMUNE LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hunter, Alan Gaithersburg, US 14 28
Linke, Thomas Gaithersburg, US 13 35
Sathish, Hasige Gaithersburg, US 9 55
Shah, Ambarish Gaithersburg, US 15 114
Thompson, Christopher Gaithersburg, US 112 2350
Wang, William K Gaithersburg, US 9 36

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