HUMANIZED ANTI-HMGB1 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF.

Mexico Patent

APP PUB NO MX-2015009547-A
SERIAL NO

2015009547

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Abstract

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The present invention provides: a humanized anti-HMGB1 antibody that binds specifically to a sequence consisting of an eight-amino-acid residue (EEEDDDDE) at the C terminal of the HMGB1 protein, and that is effective in the treatment or prophylaxis of various inflammatory diseases related to said protein; an antigen-binding fragment of said antibody; and a pharmaceutical composition including said antibody or said antigen-binding fragment thereof.

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Patent Owner(s)

Patent OwnerAddress
EVEC INCJPSAPPORO

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Inventor(s)

Inventor Name Address
TORASHIMA TAKASHI -
NISHIBORI MASAHIRO -
TAKADA KENZO SAPPORO

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