Immobilization of biologically active material with glutaraldehyde and polyazaetidine
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United States of America
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Nov 13, 1990
Grant Date -
N/A
app pub date -
Apr 23, 1990
filing date -
Jun 14, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Immobilized biologically active material in particle form is prepared by cross-linking with glutaraldehyde and polyazetidine. An aqueous dispersion or solution of biologically active material is partially cross-linked with glutaraldehyde, a wet pasty mass is recovered by dewatering and the mass is sub-divided into discrete particles. A polyazetidine prepolymer is added before, at the beginning or subsequent to partially cross-linking but prior to subdividing the pasty mass into particles, and the prepolymer is allowed to cross-link.
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