INGAP protein involved in pancreatic islet neogenesis
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United States of America Patent
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Sep 19, 2006
Grant Date -
N/A
app pub date -
Nov 13, 2000
filing date -
Feb 22, 1995
priority date (Note) -
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Abstract
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.
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