1′-substituted carba-nucleoside analogs for antiviral treatment

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United States of America Patent

PATENT NO RE46762
SERIAL NO

15288271

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Abstract

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Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.

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Patent Owner(s)

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GILEAD SCIENCES INC333 LAKSESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Butler, Thomas Carmel, US 28 841
Cho, Aesop Mountain View, US 78 3090
Kim, Choung U San Carlos, US 138 4246
Parrish, Jay P El Dorado Hills, US 36 1093
Saunders, Oliver L Clovis, US 26 1571
Zhang, Lijun Los Altos Hills, US 174 2085

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