Mitochondrially delivered anti-cancer compounds

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United States of America Patent

PATENT NO RE47300
SERIAL NO

14955297

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates to anti-cancer compounds and to methods for treating or preventing cancer. In one aspect the invention concerns mitochondrially delivered pro-oxidant anti-cancer compounds that generate reactive oxygen species and induce apoptosis of cancerous cells. The delivery moiety can be a lipophilic cation and the pro-oxidant moiety can be a pro-oxidant vitamin E analogue, such as α-tocopheryl succinate, α-tocopheryl maleate, α-tocopheryl maleyl amide, or 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)-chroman-6-yloxyacetic acid (α-tocopheryloxyacetic acid).

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Patent Owner(s)

Patent OwnerAddress
CANCURE LIMITEDSURFERS PARADISE QUEENSLAND 4217

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Neuzil, Jiri Runaway Bay, AU 7 30
Ralph, Stephen John Mermaid Waters, AU 7 101

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