Process for producing a stable low concentration, injectable solution of noradrenaline
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United States of America Patent
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Feb 21, 2023
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N/A
app pub date -
Aug 30, 2020
filing date -
Aug 30, 2020
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Abstract
In a first aspect, the present invention relates to a process for producing a stable, injectable solution with low content of noradrenaline, which includes dissolving noradrenaline and optionally an excipient in deoxygenated or degassed water, filtrating the resulting noradrenaline solution in a nitrogen current, distributing the solution in a nitrogen current, and sterilization, preferably hot. The invention further provides a stable, injectable solution with low content of noradrenaline, substantially free of anti-oxidizing and preservative agents, as well as uses thereof in the medical and pharmaceutical fields.
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