Methods of detecting a polypeptide having anaplastic lymphoma kinase activity in kidney cancer

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United States of America

PATENT NO 10551383
APP PUB NO 20150369810A1
SERIAL NO

14844832

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Abstract

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The invention provides methods to identify, diagnose, and treat kidney cancer through the detection of expression and/or activity of anaplastic lymphoma kinase (ALK). The detection of the presence of a polypeptide with ALK kinase activity (e.g., by detecting expression and/or activity of the polypeptide), identify those kidney cancers that are likely to respond to an ALK-inhibiting therapeutic.

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Patent Owner(s)

Patent OwnerAddress
CELL SIGNALING TECHNOLOGY INCDANVERS MA 01923

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Crosby, Katherine Eleanor Middleton, US 17 13
Haack, Herbert South Hamilton, US 31 73
Rimkunas, Victoria McGuinness Reading, US 12 13
Silver, Matthew Ren Rockport, US 7 9

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