Compositions for affecting weight loss
Number of patents in Portfolio can not be more than 2000
United States of America
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Mar 22, 2022
Grant Date -
Jul 18, 2019
app pub date -
Mar 25, 2019
filing date -
Mar 25, 2019
priority date (Note) -
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Abstract
Disclosed are compositions for affecting weight loss comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound causes increased agonism of a melanocortin 3 receptor (MC3-R) or a melanocortin 4 receptor (MC4-R) compared to normal physiological conditions. Also disclosed are methods of affecting weight loss, increasing energy expenditure, increasing satiety in an individual, or suppressing the appetite of an individual, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance α-MSH activity.
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