Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof

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United States of America Patent

PATENT NO 11524003
APP PUB NO 20200155515A1
SERIAL NO

16752961

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Abstract

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The invention provides α-amino esters of a hydroxypropylthiazolidine carboxamide derivative, (2S)-3-([1,1′-biphenyl]-4-ylsulfonyl)-N-[(1S)-3-hydroxy-1-phenylpropyl]-1,3-thiazolidine-2-carboxamide, as well as salts and crystal polymorphs thereof, that can be used to inhibit prostaglandin F receptor. The invention further encompasses methods of treating disorders such as preterm labor at the early gestational stage by the administration of these substances to a patient in need of treatment.

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Patent Owner(s)

Patent OwnerAddress
XOMA (US) LLC2200 POWELL STREET SUITE 310 EMERYVILLE CA 94608

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gotteland, Jean-Pierre Geneva, CH 43 136
Jorand-Lebrun, Catherine Arlington, US 52 346
Loumaye, Ernest Cologny, CH 26 236
Page, Patrick Naxos Saint-Julien-en Genevois, FR 10 33
Pohl, Oliver Plan-les-Ouates, CH 16 21
Pomel, Vincent Groisy, FR 33 134
Quattropani, Anna Rolle, CH 73 404
Schwarz, Matthias Gland, CH 65 567

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