Method of preparing low-crystallinity oltipraz or amorphous oltipraz
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United States of America Patent
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Issued Date -
Jul 28, 2005
app pub date -
Jan 27, 2005
filing date -
Jan 27, 2004
priority date (Note) -
Abandoned
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Abstract
Provided is a method of preparing low-crystallinity oltipraz or amorphous oltipraz. The method includes: obtaining a mixed solution containing oltipraz and a water-soluble polymer or a water-insoluble polymer in a solvent, the solvent being an organic solvent or purified water; and solid-dispersing the oltipraz in the polymer. In the solid-dispersing, the mixed solution may be spray dried using a spray dryer or granulated using a fluid bed granulator.
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