Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
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United States of America Patent
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Jun 3, 2003
Grant Date -
Sep 19, 2002
app pub date -
Feb 8, 2002
filing date -
Dec 31, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
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